Characterizing the Human Airway Immune Response to FluMist Vaccination

Wednesday, September 17, 2025 12:00 AM

Conditions: Healthy Young Adults; Influenza Vaccines; Influenza Vaccine Response Interventions: Biological: FluMist; Biological: inactivated influenza vaccine; Procedure: bronchoscopy Sponsors: Washington University School of Medicine; AstraZeneca Recruiting

SGLT2 Inhibitors in Geographic Atrophy

Tuesday, September 16, 2025 12:00 AM

Conditions: Retinal Degeneration; Retinal Diseases; Eye Diseases; Geographic Atrophy; Pathological Conditions, Anatomical Interventions: Drug: Dapagliflozin; Other: Matching Placebo Sponsors: Washington University School of Medicine Recruiting

Steroid Treatment for Elimination of Rebound Obstruction From Intranasal Decongestants

Thursday, September 11, 2025 12:00 AM

Conditions: Nasal Obstruction; Chronic Rhinitis Interventions: Drug: Oxymetazoline + Triamcinolone Sponsors: Washington University School of Medicine Recruiting

Precision Treatment to Promote Smoking Cessation and Survival in Oncology Patients

Wednesday, September 10, 2025 12:00 AM

Conditions: Smoking Cessation; Smoking; Physician's Role Interventions: Behavioral: Usual care; Behavioral: Precision treatment Sponsors: Washington University School of Medicine; United States Department of Defense Not yet recruiting

Small Cell Lung Cancer Irinotecan and CDC2-like Kinase Inhibition Trial (SLICK Trial)

Thursday, September 4, 2025 12:00 AM

Conditions: Small-cell Lung Cancer; Small Cell Lung Carcinoma; Small Cell Lung Cancer Interventions: Drug: Cirtuvivint; Drug: Irinotecan Sponsors: Washington University School of Medicine; Biosplice Therapeutics, Inc. Not yet recruiting

Obstructive Sleep Apnea Non-PAP Outcomes and Viable Alternatives

Thursday, September 4, 2025 12:00 AM

Conditions: Obstructive Sleep Apnea Interventions: Device: MAD; Device: HGNS Sponsors: Washington University School of Medicine Not yet recruiting

Zanzalintinib Combined With Eribulin in Advanced Liposarcoma and Leiomyosarcoma

Tuesday, September 9, 2025 12:00 AM

Conditions: Advanced Leiomyosarcoma; Adipocytic Sarcoma; Advanced Liposarcoma Interventions: Drug: Zanzalintinib; Drug: Eribulin Sponsors: Washington University School of Medicine; Exelixis Not yet recruiting

Milk Fat Globule Membrane-Enhanced RUTF for Children With Severe Acute Malnutrition

Tuesday, September 9, 2025 12:00 AM

Conditions: Severe Acute Malnutrition; Cognitive Impairment; Kwashiorkor; Severe Wasting Interventions: Dietary Supplement: MFGM-RUTF (milk fat globule membrane ready-to-use therapeutic food); Dietary Supplement: S-RUTF (standard ready-to-use ...